The impact of cyclizine on maternal-fetal bonding
Cyclizine is an antihistamine that is used to treat nausea and vomiting. It is also used to treat vertigo. Cyclizine is in a class of medications called antihistamines. It works by blocking a histamine that is produced during an allergic reaction.
Cyclizine hydrochloride was first synthesized in 1948. It is available as a tablet, syrup, or suppository. It is also available as an injection. The injectable form is used when a person cannot take the medication by mouth. Cyclizine hydrochloride is also available as an oral solution.
Cyclizine is used to treat nausea and vomiting due to various causes, including:
• Motion sickness
• Morning sickness
• Vertigo
• Chemotherapy
• Anesthesia
Cyclizine may also be used for purposes not listed in this medication guide.
Important Information
You should not use cyclizine if you are allergic to it, or if you have urination problems, glaucoma, or an enlarged prostate.
Before taking this medicine
You should not use cyclizine if you are allergic to it, or if you have:
urination problems;
glaucoma; or
an enlarged prostate.
To make sure cyclizine is safe for you, tell your doctor if you have ever had:
liver disease;
kidney disease;
asthma, COPD, or other breathing disorder;
a blockage in your stomach or intestines;
a blood disorder; or
if you take a blood thinner (warfarin, Coumadin, Jantoven).
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Cyclizine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take cyclizine?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take this medicine with a full glass of water.
Do not take cyclizine with fruit juice (such as apple, orange, or grapefruit).
To take a cyclizine suppository:
Remove the wrapper. Wet the tip of the suppository with cool water. Lie down on your side and gently insert the suppository into the rectum. Apply gentle pressure to insert the suppository past the anal sphincter. Hold the suppository in place for a few minutes. Try to avoid having a bowel movement for at least 1 hour after you insert the suppository.
To take an oral solution:
Measure the oral solution with a marked measuring spoon, oral syringe, or cup. Do not use a regular table spoon. The oral solution may be placed directly into the mouth, or mixed with water, milk, baby formula, fruit juice, or ginger ale.
To take an oral tablet:
Swallow the tablet whole with a full glass of water. Do not split the tablet.
To take an injectable solution:
This medicine is given as a shot under your skin or into a muscle. A healthcare provider will give you this injection.
Cyclizine is usually given as an injection at your doctor’s office, hospital, or clinic. If you will be using cyclizine at home, a health care provider will teach you how to use it. Be sure you understand how to use cyclizine. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
To treat nausea and vomiting: For adults and children older than 12 years of age, the usual dose is 25 to 100 mg injected into a muscle every four to six hours, or 50 mg injected under the skin every four to six hours.
To treat vertigo: The usual dose is 50 mg injected into a muscle every eight hours, or 100 mg injected under the skin every eight hours.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Cyclizine will not treat a viral infection such as the flu or a common cold.
Call your doctor if your symptoms do not improve, or if they get worse.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Since cyclizine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose can cause severe drowsiness.
Symptoms of a cyclizine overdose may include:
drowsiness;
confusion;
blurred vision; or
fast, slow, or uneven heart rate.
What should I avoid while taking cyclizine?
Taking cyclizine may make your vision temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until your vision is clear.
Cyclizine may cause drowsiness. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Avoid drinking fruit juice (such as apple, orange, or grapefruit) while you are taking this medicine.
Cyclizine side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
drowsiness, confusion, or sedation;
blurred vision;
fast, slow, or pounding heartbeats;
breathing problems;
seizure (convulsions); or
little or no urination.
Common side effects may include:
drowsiness;
dry mouth; or
upset stomach.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect cyclizine?
Taking cyclizine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking cyclizine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Other drugs may interact with cyclizine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using..Visit Site
The correspondence between cyclizine and morning sickness
Cyclizine is an antihistamine that is used to treat nausea and vomiting. It is also used to treat vertigo (a type of dizziness). Cyclizine is used to treat morning sickness in pregnant women. It is also used to prevent and treat motion sickness. Cyclizine works by blocking the action of histamine, a substance in the body that causes nausea and vomiting.
Cyclizine is available under the following different brand names: Marezine, and Cyclizine Hydrochloride.
Dosages of Cyclizine:
Adult and Pediatric Dosages:
-Oral: 1 to 2 mg every four hours as needed or 30 to 50 mg every four to six hours as needed
-Rectal: 25 to 100 mg every four to six hours as needed
-Injection: 25 to 100 mg every four to six hours as needed
Adult Dosage for Motion Sickness:
-Oral: 50 mg every four to six hours as needed or 30 minutes before exposure to motion, then every eight hours as needed while in motion
-Injection: 25 to 50 mg 30 minutes before exposure to motion, then every eight hours as needed while in motion
Pediatric Dosage for Motion Sickness:
-Oral: 1 mg/kg (0.5 mg/lb) every four to six hours as needed or 30 minutes before exposure to motion, then every eight hours as needed while in motion
-Injection: 0.5 to 1 mg/kg (0.25 to 0.5 mg/lb) 30 minutes before exposure to motion, then every eight hours as needed while in motion
– IV: 0.5 to 1 mg/kg (0.25 to 0.5 mg/lb) slowly over five to 10 minutes, then every eight hours as needed while in motion
What are the side effects of Cyclizine?
Common side effects of Cyclizine include:
-Drowsiness
-Dizziness
-Blurred vision
-Dry mouth
-Nausea
-Vomiting
-Constipation
-Increased appetite
-Weight gain
Side effects that are more serious include:
-Agitation
-Anxiety
-Hallucinations
-Confusion
-Seizures
-Yellowing of the skin or eyes
-Dark urine
-Fever
-Rash
-Hives
-Difficulty breathing or swallowing
-Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
If you experience any of the following side effects, call your doctor immediately:
-Severe dizziness
-Fainting
-Fast, pounding, or irregular heartbeat
-Severe drowsiness
-Seizures
-Yellowing of the skin or eyes
-Dark urine
-Fever
-Rash
-Hives
-Difficulty breathing or swallowing
-Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
What is the most important information I should know about Cyclizine?
-Cyclizine may cause drowsiness or dizziness. Do not drink alcohol or take other medications that cause drowsiness or dizziness while taking cyclizine.
-Do not take more cyclizine than is prescribed by your doctor.
-Cyclizine may be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.
-Swallow the tablets whole. Do not chew, divide, or crush the tablets.
-Cyclizine may interact with other medications. Tell your doctor all medications you are taking.
-During pregnancy, cyclizine should be used only when prescribed by your doctor. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.
We used pregnancysicknesssuport.org.uk to write this article about cyclizine when pregnant. Official source.